US 11,890,106 B2
Measuring wound healing
Atte Kekonen, Tampere (FI); Mikael Bergelin, Turku (FI); Jan-Erik Eriksson, Turku (FI); and Max Johansson, Turku (FI)
Assigned to CutoSense Oy, Turku (FI)
Appl. No. 16/618,130
Filed by CutoSense Oy, Turku (FI)
PCT Filed May 31, 2018, PCT No. PCT/EP2018/064353
§ 371(c)(1), (2) Date Nov. 28, 2019,
PCT Pub. No. WO2018/220121, PCT Pub. Date Dec. 6, 2018.
Claims priority of application No. 17173840 (EP), filed on May 31, 2017.
Prior Publication US 2020/0170565 A1, Jun. 4, 2020
Int. Cl. A61B 5/00 (2006.01); A61B 5/0531 (2021.01)
CPC A61B 5/445 (2013.01) [A61B 5/0531 (2013.01); A61B 5/68 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A method for measuring wound healing, comprising:
measuring a wound transfer impedance by a first tetrapolar arrangement of electrodes arranged on both sides of a wound; wherein the first tetrapolar arrangement of electrodes comprises two current feeding electrodes and two voltage sensing electrodes, wherein the measuring of the wound transfer impedance comprises:
applying, by the two current feeding electrodes, an excitation signal, and
measuring, by the voltage sensing electrodes, an impedance based on a voltage difference induced by the excitation signal,
measuring a reference transfer impedance by a second tetrapolar arrangement of electrodes arranged on one side of the wound; wherein the second tetrapolar arrangement of electrodes comprises two current feeding electrodes and two voltage sensing electrodes, wherein the measuring of the reference transfer impedance comprises:
applying, by the two current feeding electrodes, an excitation signal, and
measuring, by the voltage sensing electrodes, an impedance based on a voltage difference induced by the excitation signal,
wherein the wound transfer impedance and the reference transfer impedance are measured over a frequency range, and
determining, by a controller, at least one level of the wound healing on the basis of a ratio between the wound transfer impedance and the reference transfer impedance and a change of said ratio over at least part of the frequency range,
wherein the change of said ratio meets a predefined threshold.