CPC G01N 33/9473 (2013.01) [C07C 229/28 (2013.01); C07C 233/36 (2013.01); C07C 233/47 (2013.01); C07C 321/04 (2013.01); C07C 323/25 (2013.01); C07K 16/44 (2013.01); G01N 33/53 (2013.01); G01N 33/5308 (2013.01); A61K 2039/505 (2013.01); A61K 2039/60 (2013.01); C07C 2601/12 (2017.05); C07C 2601/14 (2017.05)] | 8 Claims |
1. A compound or a salt thereof for use in a gabapentin immunoassay for detecting the presence or absence of gabapentin in a sample, wherein the compound has the structure:
wherein:
R1, R2, or R3 is -X-W-L-Z,
when R1 is -X-W-L-Z, X is NH, and R2 is —OH, and R3 is —H,
when R2 is -X-W-L-Z, X is NH, R1 is —NH2, and R3 is —H, and
when R3 is -X-W-L-Z, X is a heteroatom or lower alkyl group, R1 is —NH2, and R2 is —OH;
W is a lower alkyl group or a carbonyl group;
L is a linker or at least one bond between W and Z; and
Z is a detectable label, wherein the detectable label comprises a fluorophore, a radioisotope, or a metal particle and wherein said fluorophore is selected from the group consisting of fluorescein derivatives, rhodamine derivatives, phycoerythrin, and Texas red.
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