	US 11,867,341 B2
	Treating fluidic channels
Eric Hanson, Carlsbad, CA (US); and Eric Bruner, La Jolla, CA (US)
Assigned to ACULON INC., San Diego, CA (US)
Filed by ACULON, INC, San Diego, CA (US)
Filed on Nov. 27, 2019, as Appl. No. 16/698,503.
Application 16/698,503 is a division of application No. 13/507,981, filed on Aug. 10, 2012, abandoned.
Claims priority of provisional application 61/574,935, filed on Aug. 11, 2011.
Prior Publication US 2020/0166173 A1, May 28, 2020
Int. Cl. B05D 7/00 (2006.01); F16L 58/08 (2006.01); B05D 1/18 (2006.01); B82Y 40/00 (2011.01); B82Y 30/00 (2011.01); B05D 7/22 (2006.01)

CPC F16L 58/08 (2013.01) [B05D 1/185 (2013.01); B05D 7/225 (2013.01); B05D 7/544 (2013.01); B82Y 30/00 (2013.01); B82Y 40/00 (2013.01); B05D 7/222 (2013.01); B05D 2201/02 (2013.01); B05D 2202/00 (2013.01); B05D 2254/04 (2013.01)]

15 Claims

1. A method of depositing a coating of nanometer dimensions onto interior walls within a fluidic channel comprising:

a) Providing an open fluidic channel with an open end having a nozzle or dispensing device, wherein fluid flows from a source through the fluidic channel to the open end with the nozzle or dispensing device;

b) contacting the interior walls of the fluidic channel either directly, or indirectly through an intermediate organometallic coating, with a solution comprising a diluent and an organophosphorus acid by pumping the solution through the fluidic channel;

c) removing the solution from the fluidic channel; and

d) evaporating the diluent from the interior walls of the fluidic channel to form a self-assembled monolayer of the organophosphorus acid chemically bonded via an ionic or covalent bond with reactive groups on one of the interior walls of the fluidic channel or the intermediate organometallic layer.