CPC C12Q 1/6886 (2013.01) [G01N 1/31 (2013.01); G01N 15/1475 (2013.01); G01N 33/5094 (2013.01); G01N 33/57484 (2013.01); G01N 33/582 (2013.01); C12Q 1/6883 (2013.01); G01N 15/1468 (2013.01); G01N 2015/1472 (2013.01); G01N 2333/4742 (2013.01); G01N 2333/70589 (2013.01); G06T 7/0012 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/30096 (2013.01); G06T 2207/30101 (2013.01)] | 12 Claims |
1. A computer program product for identifying candidate target cells within a biological fluid specimen, the computer program product tangibly embodied in a non-transitory computer readable medium, comprising instructions to cause a processor to:
receive a digital image of the biological fluid specimen;
identify one or more candidate regions of pixels in the digital image, wherein the instructions to identify the one or more candidate regions include instructions to identify connected regions of pixels of a minimum intensity having a size between a minimum size and a maximum size and an aspect ratio that meets a threshold; and
for each candidate region of at least one of the one or more candidate region
analyze the image to identify distinct gray levels in the candidate region,
performing a count of the gray levels, and
determine whether the count of gray levels is more than a threshold number, and if the count of gray levels is more than the threshold number then continue to treat the portion of the image as a candidate for classification.
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