US 11,866,746 B2
Compositions comprising a variant Cas12i4 polypeptide and uses thereof
Shaorong Chong, Arlington, MA (US); Wei-Cheng Lu, Cambridge, MA (US); Brendan Jay Hilbert, Natick, MA (US); Quinton Norman Wessells, Cambridge, MA (US); Tia Marie Ditommaso, Waltham, MA (US); and Anthony James Garrity, Hingham, MA (US)
Assigned to ARBOR BIOTECHNOLOGIES, INC., Cambridge, MA (US)
Filed by ARBOR BIOTECHNOLOGIES, INC., Cambridge, MA (US)
Filed on Dec. 30, 2022, as Appl. No. 18/148,818.
Application 18/148,818 is a continuation of application No. PCT/US2022/016214, filed on Feb. 11, 2022.
Claims priority of provisional application 63/154,437, filed on Feb. 26, 2021.
Claims priority of provisional application 63/148,421, filed on Feb. 11, 2021.
Prior Publication US 2023/0295589 A1, Sep. 21, 2023
Int. Cl. C12N 9/22 (2006.01); C12N 15/11 (2006.01); C12N 15/10 (2006.01); C12N 5/071 (2010.01); C12N 15/90 (2006.01)
CPC C12N 9/22 (2013.01) [C12N 5/0686 (2013.01); C12N 15/102 (2013.01); C12N 15/11 (2013.01); C12N 15/907 (2013.01); C12N 2310/20 (2017.05); C12N 2800/80 (2013.01)] 20 Claims
 
1. A variant Cas12i4 polypeptide comprising the sequence set forth in SEQ ID NO: 4.