US 11,866,723 B2
Plant virus movement proteins and methods of using same
Gulilat Gebeyehu, Potomac, MD (US); and Joel Jessee, Mount Airy, MD (US)
Assigned to MOLECULAR TRANSFER INC., Gaithersburg, MD (US)
Filed by MOLECULAR TRANSFER INC., Gaithersburg, MD (US)
Filed on Jan. 20, 2020, as Appl. No. 16/747,443.
Application 16/747,443 is a continuation of application No. 15/446,578, filed on Mar. 1, 2017, granted, now 10,538,784.
Claims priority of provisional application 62/303,278, filed on Mar. 3, 2016.
Claims priority of provisional application 62/302,155, filed on Mar. 1, 2016.
Prior Publication US 2020/0283795 A1, Sep. 10, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 48/00 (2006.01); C12N 15/85 (2006.01); C12N 15/87 (2006.01); C07K 14/005 (2006.01); C07K 14/415 (2006.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01); C12N 15/88 (2006.01); C12N 15/90 (2006.01)
CPC C12N 15/85 (2013.01) [A61K 48/0041 (2013.01); C07K 14/005 (2013.01); C07K 14/415 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/87 (2013.01); C12N 15/88 (2013.01); C12N 15/907 (2013.01); C12N 2310/20 (2017.05); C12N 2810/10 (2013.01); C12N 2810/65 (2013.01)] 15 Claims
 
1. A transfection complex for transfection of a eukaryotic cell comprising a transfection agent and a peptide sequence selected from SEQ ID NOs: 540-547, 549, 551, 552, 559-564, 566, and 568-571 optionally linked to a nucleic acid binding moiety, wherein the transfection agent is a lipoplex or lipid aggregate comprising at least one piperazine based cationic lipid.