	US 11,866,492 B2
	Antibody specifically binding to FOLR1 and uses thereof
Soon Jae Park, Daejeon (KR); Hye-Shin Chung, Daejeon (KR); and Sunbae Lee, Daejeon (KR)
Assigned to ALTEOGEN, INC., Daejeon (KR)
Appl. No. 16/980,074
Filed by ALTEOGEN, INC., Daejeon (KR)
PCT Filed Mar. 13, 2019, PCT No. PCT/KR2019/002911 § 371(c)(1), (2) Date Sep. 11, 2020, PCT Pub. No. WO2019/177372, PCT Pub. Date Sep. 19, 2019.
Claims priority of application No. 10-2018-0029762 (KR), filed on Mar. 14, 2018.
Prior Publication US 2021/0009685 A1, Jan. 14, 2021
Int. Cl. C07K 16/28 (2006.01); A61K 47/68 (2017.01); G01N 33/574 (2006.01); C07K 16/02 (2006.01)

CPC C07K 16/02 (2013.01) [A61K 47/6849 (2017.08); G01N 33/57492 (2013.01); C07K 2317/732 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); G01N 2333/705 (2013.01)]

10 Claims

1. An antibody or antigen-binding fragment thereof that binds specifically to folate receptor-a (FOLR1), said antibody or antigen-binding fragment thereof comprising:

a heavy-chain variable region of SEQ ID NO: 1 and a light-chain variable region of SEQ ID NO: 32; or

a heavy-chain variable region of SEQ ID NO: 1 and a light-chain variable region of SEQ ID NO: 33; or

a heavy-chain variable region of SEQ ID NO: 1 and a light-chain variable region of SEQ ID NO: 34; or

a heavy-chain variable region of SEQ ID NO: 31 and a light-chain variable region of SEQ ID NO: 2; or

a heavy-chain variable region of SEQ ID NO: 31 and a light-chain variable region of SEQ ID NO: 32.