CPC C07D 209/32 (2013.01) [C07D 209/12 (2013.01); C07D 209/14 (2013.01)] | 28 Claims |
1. A compound of Formula (I), or a pharmaceutically acceptable salt thereof:
wherein:
R1 is methoxy or hydrogen;
R2 is —C(O)R4, —C(O)OCH(R5)OC(O)OR6,
R4 is alkyl, which is substituted with —N(R18)R19;
R5 is hydrogen, alkyl, or cycloalkyl;
R6 is alkyl, cycloalkyl, or —CH(RA1)NH2;
RA1 is alkyl or an amino acid side chain;
RA5 is —N(R18)R19 or —N(R13)C(O)R14;
R13 is hydrogen; R14 is alkyl;
R15 is alkyl, heteroalkyl, cycloalkyl, aryl, or heteroaryl, each of which is unsubstituted or substituted with one or more RB; and
each of R18 and R19 is independently hydrogen or alkyl.
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