CPC B01L 3/5027 (2013.01) [B81B 7/00 (2013.01); B01L 2200/16 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/1827 (2013.01); B01L 2400/0442 (2013.01)] | 20 Claims |
1. A microfluidic reaction system comprising
a microfluidic die comprising a microfluidic volume comprising a microfluidic channel having a dimension on an order of 10 microns;
a proud structure rising from a floor of the microfluidic volume;
a port connected to the microfluidic volume for receiving a fluid; and
a freeze-dried reaction agent, wherein external surfaces of the proud structure that face the microfluidic volume are coated with the freeze-dried reaction agent.
|
16. A method of making the microfluidic reaction system of claim 1, the method comprising:
forming a microfluidic volume in a microfluidic die;
forming a proud structure rising from a floor of the microfluidic volume;
introducing a reaction agent into the microfluidic volume; and
freeze-drying the reaction agent within the microfluidic volume to coat external surfaces of the proud structure that face the microfluidic volume, the freeze-drying comprising:
freezing the reaction agent during a first freezing period; and
drying the reaction agent during two drying periods, a first drying period having a lower temperature than a second drying period.
|