CPC A61N 5/1031 (2013.01) [C12Q 1/6883 (2013.01); A61N 2005/1032 (2013.01); C12Q 2600/158 (2013.01)] | 18 Claims |
1. A computer software configured to integrate with a radiation therapy treatment planning system, the computer software being configured to:
assign a radiation sensitivity index (RSI) of a subject's tumor based at least in part on expression levels of one or more signature genes in the tumor;
calculate a recommended personalized radiation dosage (RxRSI) for the subject based at least in part on a pre-determined genomic adjusted radiation dose (GARD) value and the RSI; and
provide, to the radiation therapy treatment planning system, the recommended RxRSI as a radiation therapy dose for a radiation plan,
wherein the computer software is embodied on a non-transitory computer readable medium, and
wherein the pre-determined GARD value is about 33 for non-small cell lung cancer.
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