US 11,865,298 B2
Systems and techniques for generating, infusing, and controlling radioisotope delivery
Adrian Nunn, Lambertville, NJ (US); Clif Moyers, Oak Ridge, TN (US); Andrew Schimmoeller, Plain City, OH (US); Brian Cherundolo, White Marsh, MD (US); and Tarah Bolas, Knoxville, TN (US)
Assigned to Bracco Diagnostics Inc., Monroe Township, NJ (US)
Appl. No. 16/334,887
Filed by BRACCO DIAGNOSTICS INC., Monroe Township, NJ (US)
PCT Filed Sep. 20, 2017, PCT No. PCT/US2017/052537
§ 371(c)(1), (2) Date Mar. 20, 2019,
PCT Pub. No. WO2018/057636, PCT Pub. Date Mar. 29, 2018.
Claims priority of provisional application 62/397,025, filed on Sep. 20, 2016.
Claims priority of provisional application 62/397,022, filed on Sep. 20, 2016.
Claims priority of provisional application 62/397,026, filed on Sep. 20, 2016.
Prior Publication US 2020/0030523 A1, Jan. 30, 2020
Int. Cl. A61M 5/00 (2006.01); A61K 51/12 (2006.01); G21F 5/015 (2006.01); G21G 1/00 (2006.01); G21G 4/08 (2006.01); A61M 5/14 (2006.01); A61M 5/162 (2006.01); A61M 5/168 (2006.01); G01T 1/20 (2006.01); G21H 5/02 (2006.01); G01T 7/00 (2006.01); A61N 5/10 (2006.01); A61M 5/142 (2006.01); G01T 1/16 (2006.01)
CPC A61M 5/007 (2013.01) [A61K 51/121 (2013.01); A61K 51/1282 (2013.01); A61M 5/142 (2013.01); A61M 5/1408 (2013.01); A61M 5/162 (2013.01); A61M 5/16827 (2013.01); A61M 5/16881 (2013.01); A61N 5/1007 (2013.01); G01T 1/20 (2013.01); G01T 7/005 (2013.01); G21F 5/015 (2013.01); G21G 1/0005 (2013.01); G21G 4/08 (2013.01); G21H 5/02 (2013.01); A61K 2123/00 (2013.01); A61M 2205/18 (2013.01); A61M 2205/3313 (2013.01); A61M 2205/3389 (2013.01); A61M 2205/702 (2013.01); A61N 2005/1021 (2013.01); G01T 1/1603 (2013.01); G21G 2001/0031 (2013.01)] 38 Claims
OG exemplary drawing
 
1. An infusion system comprising:
a frame that carries a beta detector, a gamma detector, and a controller communicatively coupled to the beta detector and the gamma detector,
wherein the frame is further configured to receive a strontium-rubidium radioisotope generator that generates a radioactive eluate via elution,
the beta detector is positioned to measure beta emissions emitted from the radioactive eluate,
the gamma detector is positioned to measure gamma emissions emitted from the radioactive eluate, and
the controller is configured to determine an activity of rubidium in the radioactive eluate based on the beta emissions measured by the beta detector and determine an activity of strontium in the radioactive eluate based on the gamma emissions measured by the gamma detector.