US 11,865,289 B2
On-body microsensor for biomonitoring
Ashwin Pushpala, San Francisco, CA (US); Alan Szmodis, San Francisco, CA (US); Matthew Chapman, Oakland, CA (US); Weldon Hall, San Francisco, CA (US); Scott Miller, San Francisco, CA (US); and Hooman Hafezi, San Francisco, CA (US)
Assigned to One Drop Biosensor Technologies, LLC, New York, NY (US)
Filed by One Drop Biosensor Technologies, LLC, New York, NY (US)
Filed on Nov. 2, 2021, as Appl. No. 17/517,635.
Application 17/517,635 is a continuation of application No. 17/125,999, filed on Dec. 17, 2020.
Application 17/125,999 is a continuation of application No. 16/886,742, filed on May 28, 2020, granted, now 11,123,532, issued on Sep. 21, 2021.
Application 16/886,742 is a continuation of application No. 16/722,977, filed on Dec. 20, 2019.
Application 16/722,977 is a continuation of application No. 14/876,692, filed on Oct. 6, 2015, granted, now 10,549,080, issued on Feb. 4, 2020.
Application 14/876,692 is a continuation of application No. 14/211,404, filed on Mar. 14, 2014, granted, now 9,182,368, issued on Nov. 10, 2015.
Claims priority of provisional application 61/905,583, filed on Nov. 18, 2013.
Claims priority of provisional application 61/781,754, filed on Mar. 14, 2013.
Prior Publication US 2022/0054813 A1, Feb. 24, 2022
Int. Cl. A61M 37/00 (2006.01); A61B 5/00 (2006.01); G01N 27/327 (2006.01); A61B 5/15 (2006.01); A61B 5/145 (2006.01); A61B 5/1486 (2006.01); A61B 5/1495 (2006.01); C12Q 1/00 (2006.01); A61M 25/00 (2006.01)
CPC A61M 37/0015 (2013.01) [A61B 5/1495 (2013.01); A61B 5/14503 (2013.01); A61B 5/14514 (2013.01); A61B 5/14532 (2013.01); A61B 5/14546 (2013.01); A61B 5/14865 (2013.01); A61B 5/150022 (2013.01); A61B 5/150282 (2013.01); A61B 5/150427 (2013.01); A61B 5/150969 (2013.01); A61B 5/150984 (2013.01); A61B 5/4839 (2013.01); A61B 5/685 (2013.01); C12Q 1/006 (2013.01); G01N 27/3271 (2013.01); A61B 2562/028 (2013.01); A61B 2562/12 (2013.01); A61B 2562/125 (2013.01); A61M 25/00 (2013.01); A61M 2037/0023 (2013.01); A61M 2037/0046 (2013.01); A61M 2037/0053 (2013.01); Y10T 29/49117 (2015.01)] 27 Claims
OG exemplary drawing
 
1. A method for manufacturing analyte sensing microneedles, the method comprising:
removing material from needle bodies to form sharp tips of microneedles; and
forming at least one layer along at least one of the sharp tips of a respective one of the microneedles, which has an electrically conductive inner portion and an electrically insulating material surrounding the electrically conductive inner portion, wherein the insulating material defines an outer skin-contacting surface of the respective microneedles and exposes the at least one layer is configured to detect at least one analyte in interstitial fluid when the microneedles are positioned within a user's skin.