US 11,865,197 B2
Cosmetic compositions having stabilized retinol
Jonathan James Faig, Sayreville, NJ (US); David Chan, Edison, NJ (US); and Susan Halpern, Basking Ridge, NJ (US)
Assigned to L'OREAL, Paris (FR)
Filed by L'OREAL, Paris (FR)
Filed on Jun. 30, 2020, as Appl. No. 16/916,496.
Prior Publication US 2021/0401697 A1, Dec. 30, 2021
Int. Cl. A61K 8/34 (2006.01); A61K 8/06 (2006.01); A61K 8/37 (2006.01); A61K 8/49 (2006.01); A61K 8/73 (2006.01); A61K 8/41 (2006.01)
CPC A61K 8/342 (2013.01) [A61K 8/062 (2013.01); A61K 8/375 (2013.01); A61K 8/41 (2013.01); A61K 8/498 (2013.01); A61K 8/732 (2013.01); A61K 2800/87 (2013.01)] 22 Claims
 
1. A cosmetic composition comprising:
(a) about 0.1 to about 2 wt. % of retinol;
(b) about 0.05 to about 0.8 wt. % of pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate;
(c) about 0.05 to about 2 wt. % of trisodium ethylenediamine disuccinate;
(d) about 0.5 to about 4 wt. % of polyglyceryl-3 methylglucose distearate;
(e) about 0.9 to about 5 wt. % of sodium polyacrylate
(f) about 1 to about 8 wt. % of an oil phase,
(g) water; and
(j) about 5 to about 25 wt. % of one or more polyols having from 3 to 16 carbon atoms,
wherein the cosmetic composition is an oil-in-water emulsion,
the composition does not phase separate and retains at least 90 wt. % of the retinol after storage for 8 weeks at 45° C. in a light-resistant glass container without protective packaging, and
all weight percentages are based on the total weight of the cosmetic composition.