	US 11,865,172 B2
	Materials and methods for respiratory disease control in canines
Patti Cynthia Crawford, Gainesville, FL (US); Paul J. Gibbs, Gainesville, FL (US); Edward J. Dubovi, Ithaca, NY (US); Ruben Omar Donis, Atlanta, GA (US); Jacqueline Katz, Atlanta, GA (US); Alexander I. Klimov, Atlanta, GA (US); Nallakannu P. Lakshmanan, Millsboro, DE (US); Melissa Anne Lum, Millsboro, DE (US); Daniel Ghislena Emiel Goovaerts, Boxmeer (NL); Mark William Mellencamp, Desoto, KS (US); Nancy J. Cox, Atlanta, GA (US); and William L. Castleman, Gainesville, FL (US)
Assigned to UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC., Gainesville, FL (US); CORNELL RESEARCH FOUNDATION, INC., Ithaca, NY (US); and THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, CENTERS FOR DISEASE CONTROL AND PREVENTION, Atlanta, GA (US)
Filed by UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC., Gainesville, FL (US); CORNELL RESEARCH FOUNDATION, INC., Ithaca, NY (US); and The Government of The United States of America as represented by The Secretary of the Department of, Atlanta, GA (US)
Filed on Sep. 10, 2021, as Appl. No. 17/471,370.
Application 16/382,429 is a division of application No. 15/888,715, filed on Feb. 5, 2018, granted, now 10,258,686, issued on Apr. 16, 2019.
Application 15/888,715 is a division of application No. 14/507,332, filed on Oct. 6, 2014, granted, now 9,913,892, issued on Mar. 13, 2018.
Application 14/507,332 is a division of application No. 13/066,651, filed on Apr. 19, 2011, granted, now 9,345,758, issued on May 24, 2016.
Application 13/066,651 is a division of application No. 11/584,818, filed on Oct. 19, 2006, granted, now 7,959,929, issued on Jun. 14, 2011.
Application 17/471,370 is a continuation of application No. 16/382,429, filed on Apr. 12, 2019, granted, now 11,160,859.
Application 11/584,818 is a continuation in part of application No. 11/409,416, filed on Apr. 21, 2006, abandoned.
Claims priority of provisional application 60/779,080, filed on Mar. 3, 2006.
Claims priority of provisional application 60/761,451, filed on Jan. 23, 2006.
Claims priority of provisional application 60/759,162, filed on Jan. 14, 2006.
Claims priority of provisional application 60/754,881, filed on Dec. 29, 2005.
Claims priority of provisional application 60/728,449, filed on Oct. 19, 2005.
Claims priority of provisional application 60/673,443, filed on Apr. 21, 2005.
Prior Publication US 2022/0105171 A1, Apr. 7, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 39/145 (2006.01); A61K 39/12 (2006.01); C07K 14/005 (2006.01); C07K 16/10 (2006.01); C12N 7/00 (2006.01); C12Q 1/70 (2006.01); G01N 33/569 (2006.01); C12N 15/86 (2006.01); A61K 39/00 (2006.01)

CPC A61K 39/145 (2013.01) [A61K 39/12 (2013.01); C07K 14/005 (2013.01); C07K 16/1018 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); C12Q 1/701 (2013.01); G01N 33/56983 (2013.01); A61K 2039/5252 (2013.01); A61K 2039/53 (2013.01); A61K 2039/552 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/55566 (2013.01); C12N 2710/24043 (2013.01); C12N 2760/16121 (2013.01); C12N 2760/16122 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16151 (2013.01); C12N 2760/16171 (2013.01); G01N 2333/11 (2013.01)]

11 Claims

1. A reassortant virus comprising a donor influenza virus polynucleotide sequence comprising at least one gene, genomic segment, or a polynucleotide encoding a canine influenza virus protein selected from the group consisting of HA, NA, NP, MA, PB1, PB2, PA, and NS, or a functional or immunogenic fragment thereof and comprising a nucleotide sequence selected from the group consisting of SEQ ID NOs: 1, 3, 5, 7, 9, 11, 13, 15, 17, 19, 21, 23, 25, 27, 29, 31, 47, 49, 51, 53, 55, 57, 59, 61, 63, 65, 67, 69, 71, 73, 75, and 77 and a recipient influenza virus genome from a second influenza virus.