US 11,865,171 B2
Foot-and-mouth disease vaccine
Paul Joseph Dominowski, Kalamazoo, MI (US); John Morgan Hardham, Kalamazoo, MI (US); James Alan Jackson, Kalamazoo, MI (US); Cyril Gerard Gay, Bethesda, MD (US); Luis Leandro Rodriguez, Niantic, CT (US); Peter William Krug, East Setauket, NY (US); and Aida Elizabeth Rieder, Westbrook, CT (US)
Assigned to Zoetis Services LLC, Parsippany, NJ (US); and United States of America, as represented by the Secretary of Agriculture, Washington, DC (US)
Filed by Zoetis Services LLC, Parsippany, NJ (US); and United States of America, as Represented by the Secretary of Agriculture, Washington, DC (US)
Filed on Feb. 19, 2021, as Appl. No. 17/180,223.
Application 17/180,223 is a continuation of application No. 16/374,105, filed on Apr. 3, 2019, granted, now 10,967,058.
Application 16/374,105 is a continuation of application No. 15/543,630, granted, now 10,478,487, issued on Nov. 19, 2019, previously published as PCT/US2016/013587, filed on Jan. 15, 2016.
Claims priority of provisional application 62/104,314, filed on Jan. 16, 2015.
Prior Publication US 2022/0088173 A1, Mar. 24, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 39/135 (2006.01); A61K 39/12 (2006.01); A61K 39/39 (2006.01); A61K 39/00 (2006.01)
CPC A61K 39/135 (2013.01) [A61K 39/12 (2013.01); A61K 39/39 (2013.01); A61K 2039/5252 (2013.01); A61K 2039/552 (2013.01); A61K 2039/555 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/55511 (2013.01); A61K 2039/55561 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/55583 (2013.01); C12N 2770/32034 (2013.01); C12N 2770/32134 (2013.01)] 21 Claims
 
1. A method of herd management, comprising administering to each member in said herd an immunogenic composition wherein said immunogenic composition comprises: a) antigen component comprising between 6 and 20 μg of FMD (Foot-and-Mouth Disease) virus per dose; b) an emulsion containing an oil; c) 75-200 μg of a CpG-containing immunostimulatory oligonucleotide per dose; d) 75-200 mg of a polycationic carrier per dose, and wherein further, upon suspected contact with FMD infection, the vaccinated members of said herd are not slaughtered.