US 11,865,086 B2
Cinnamaldehyde derivative compounds and methods of use for cinnamaldehyde derivative compounds nicotine cessation
John P. Harrelson, Forest Grove, OR (US); and Deepa A. Rao, Beaverton, OR (US)
Assigned to PACIFIC UNIVERSITY, Forest Grove, OR (US)
Filed by Pacific University, Forest Grove, OR (US)
Filed on Jan. 28, 2022, as Appl. No. 17/649,328.
Application 17/649,328 is a continuation of application No. 16/663,291, filed on Oct. 24, 2019, granted, now 11,266,610.
Claims priority of provisional application 62/750,147, filed on Oct. 24, 2018.
Prior Publication US 2022/0142946 A1, May 12, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/11 (2006.01); A61P 25/34 (2006.01); A61K 9/00 (2006.01); A61K 31/465 (2006.01)
CPC A61K 31/11 (2013.01) [A61K 9/0053 (2013.01); A61K 31/465 (2013.01); A61P 25/34 (2018.01)] 19 Claims
OG exemplary drawing
 
1. A method for treating an individual with an addiction to nicotine, comprising administering to the individual a compound of the following chemical structure:

OG Complex Work Unit Chemistry
wherein R1 is selected from halogen, nitro, or trifluoromethyl, and
wherein a rate at which nicotine is metabolized is reduced upon administration of the compound to the individual.