CPC A61K 39/215 (2013.01) [C07K 14/165 (2013.01); C12N 15/86 (2013.01); A61K 2039/53 (2013.01); C12N 2770/20011 (2013.01)] | 14 Claims |
1. A pharmaceutical composition comprising an isolated mRNA comprising at least one coding region, encoding a spike protein (S) of a Middle East respiratory (MERS) coronavirus, said coding region being at least 90% identical to a nucleic acid sequence of SEQ ID NO: 2361, wherein the mRNA is associated with lipid nanoparticles (LNPs).
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