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1. Assembly with connectable and disconnectable elements for the reconstitution of fluid drugs and nutrients with active substances in powder, liquid or gel form, comprising a flexible bag containing a liquid solution and provided with a first valve connector with a hermetic closing valve which is openable by axial pressure and automatically hermetically reclosable when the axial pressure is stopped, at least one vial containing an active substance in powder, liquid or gel form and provided with a hermetic closing cap which is openable by axial pressure, a coupling and piercing device which is couplable to the hermetic closing cap of the vial for piercing the hermetic closing cap, and an adapter with a hollow external body interposed between the first valve connector and the coupling and piercing device, wherein the hollow external body of the adapter has a first end provided with an internal thread which is fixable by screwing to the first valve connector and an axially bored coaxial internal stem lacking end points which, due to the screwing, causes the opening of the hermetic closing valve of the first connector by axial pressure and a second end which is fixable to the coupling and piercing device, the second end providing housing for a second valve connector for connection to the coupling and piercing device, the second valve connector including the hermetic closing valve which is openable by axial pressure and automatically hermetically reclosable when the pressure is stopped, the second valve connector being axially pressable within the second end of the hollow external body and screwable into the first end of the hollow external body so that the coaxial internal stem causes the opening of the hermetic closing valve of the second valve connector by axial pressure.
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