CPC A61B 5/4064 (2013.01) [A61B 5/0031 (2013.01); A61B 5/0084 (2013.01); A61B 5/742 (2013.01); A61B 2562/0233 (2013.01); A61B 2562/046 (2013.01)] | 20 Claims |
1. A method, comprising:
implanting an implantable biosensor within a subject, the implantable biosensor comprising an array of light sources and an array of light detectors disposed on a semiconductor substrate, wherein the array of light sources and the array of light detectors are each positioned in spaced relation relative to the semiconductor substrate;
activating the array of light sources to direct light signals at a targeted tissue site in the subject;
capturing, with the array of light detectors, the light signals reflected off the targeted tissue site;
calculating a roundtrip propagation time for each of the light signals; and
comparing the roundtrip propagation time for each of the light signals against one or more corresponding prior roundtrip propagation times to determine an occurrence of a change in a cell structure at the targeted tissue site;
wherein the one or more corresponding prior roundtrip propagation times are previously generated by and stored in an external system.
|