US 11,864,865 B2
Small form factor detector module for high density diffuse optical tomography
Joseph Culver, St. Louis, MO (US); Edward Richter, St. Louis, MO (US); and Adam T. Eggebrecht, St. Louis, MO (US)
Assigned to Washington University, St. Louis, MO (US)
Filed by Joseph Culver, St. Louis, MO (US); Edward Richter, St. Louis, MO (US); and Adam T. Eggebrecht, St. Louis, MO (US)
Filed on Feb. 26, 2019, as Appl. No. 16/286,194.
Claims priority of provisional application 62/635,412, filed on Feb. 26, 2018.
Prior Publication US 2019/0261860 A1, Aug. 29, 2019
Int. Cl. A61B 5/00 (2006.01); G01B 9/02 (2022.01); G01B 9/02091 (2022.01); A61B 90/00 (2016.01); A61B 90/30 (2016.01); A61B 34/20 (2016.01)
CPC A61B 5/0066 (2013.01) [A61B 5/0035 (2013.01); A61B 5/0037 (2013.01); A61B 5/0042 (2013.01); A61B 5/6803 (2013.01); A61B 5/684 (2013.01); G01B 9/02089 (2013.01); G01B 9/02091 (2013.01); A61B 2034/2048 (2016.02); A61B 2090/0807 (2016.02); A61B 2090/306 (2016.02); A61B 2090/3614 (2016.02); A61B 2090/3937 (2016.02); A61B 2562/0233 (2013.01); A61B 2576/026 (2013.01)] 20 Claims
OG exemplary drawing
 
19. A method for obtaining a series of brain activity maps of a subject using a wearable high-diffuse optical tomography (WHD-DOT) device, the method comprising:
a) fitting the WHD-DOT device to a scalp of the subject, wherein the WHD-DOT device comprises a flexible cap, a plurality of source modules and detector modules coupled to the flexible cap in an array pattern, a plurality of brush tips, each brush tip containing one of the plurality of source modules or one of the plurality of detector modules, wherein each brush tip allows its source module or detector module to contact the scalp of the subject, and a control circuit comprising at least one control module selected from the group consisting of a microcontroller, a central processing unit, and a field programmable gate array, the at least one control module operatively coupled to the plurality of source modules and detector modules, the at least one control module configured to operate the plurality of source modules and detector modules according to at least one encoding scheme, wherein each source module and detector module comprises a housing with a maximum width ranging from about 1 mm to about 6 mm and a length ranging from about 10 mm to about 30 mm; and
b) operating, under control of the at least one control module, the plurality of source modules and detector modules to obtain a plurality of diffuse optical tomography measurements, each diffuse optical tomography measurement associated with a source-detector channel of the WHD-DOT device.