CPC A61B 5/0066 (2013.01) [A61B 5/0035 (2013.01); A61B 5/0037 (2013.01); A61B 5/0042 (2013.01); A61B 5/6803 (2013.01); A61B 5/684 (2013.01); G01B 9/02089 (2013.01); G01B 9/02091 (2013.01); A61B 2034/2048 (2016.02); A61B 2090/0807 (2016.02); A61B 2090/306 (2016.02); A61B 2090/3614 (2016.02); A61B 2090/3937 (2016.02); A61B 2562/0233 (2013.01); A61B 2576/026 (2013.01)] | 20 Claims |
19. A method for obtaining a series of brain activity maps of a subject using a wearable high-diffuse optical tomography (WHD-DOT) device, the method comprising:
a) fitting the WHD-DOT device to a scalp of the subject, wherein the WHD-DOT device comprises a flexible cap, a plurality of source modules and detector modules coupled to the flexible cap in an array pattern, a plurality of brush tips, each brush tip containing one of the plurality of source modules or one of the plurality of detector modules, wherein each brush tip allows its source module or detector module to contact the scalp of the subject, and a control circuit comprising at least one control module selected from the group consisting of a microcontroller, a central processing unit, and a field programmable gate array, the at least one control module operatively coupled to the plurality of source modules and detector modules, the at least one control module configured to operate the plurality of source modules and detector modules according to at least one encoding scheme, wherein each source module and detector module comprises a housing with a maximum width ranging from about 1 mm to about 6 mm and a length ranging from about 10 mm to about 30 mm; and
b) operating, under control of the at least one control module, the plurality of source modules and detector modules to obtain a plurality of diffuse optical tomography measurements, each diffuse optical tomography measurement associated with a source-detector channel of the WHD-DOT device.
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