US 11,864,863 B2
System, method and computer-accessible medium for accelerated, simultaneous quantitative and non-synthetic multi-contrast imaging
John Thomas Vaughan, Jr., New York, NY (US); Sairam Geethanath, New York, NY (US); Sachin Jambawalikar, New York, NY (US); Pavan Poojar, New York, NY (US); and Enlin Qian, New York, NY (US)
Assigned to THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, New York, NY (US)
Filed by John Thomas Vaughan, Jr., New York, NY (US); Sairam Geethanath, New York, NY (US); Sachin Jambawalikar, New York, NY (US); Pavan Poojar, New York, NY (US); and Enlin Qian, New York, NY (US)
Filed on Sep. 15, 2021, as Appl. No. 17/475,687.
Application 17/475,687 is a continuation of application No. PCT/US2020/022996, filed on Mar. 16, 2020.
Claims priority of provisional application 62/819,159, filed on Mar. 15, 2019.
Prior Publication US 2022/0071490 A1, Mar. 10, 2022
Int. Cl. A61B 5/00 (2006.01); A61B 5/055 (2006.01); G01R 33/56 (2006.01); G01R 33/561 (2006.01)
CPC A61B 5/0042 (2013.01) [A61B 5/055 (2013.01); G01R 33/561 (2013.01); G01R 33/5602 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A non-transitory computer-accessible medium having stored thereon computer-executable instructions for generating at least one particular image which is at least one of (i) at least one quantitative image of at least one section of at least one patient or (ii) at least one non-synthetic contrast image of the at least one section of the at least one patient, wherein, when a computer arrangement executes the instructions, the computer arrangement is configured to perform procedures comprising:
generating a first magnetic resonance (MR) signal and directing the first MR signal to the at least one patient;
receiving a second MR signal from the at least one patient that is based on the first MR signal;
generating the at least one particular image based on the second MR signal; and
generating MR information based on the second MR signal by:
pre-processing the second MR signal by compensating for a calibrated gradient delay,
scaling k-space of the second MR signal with a ratio of a field of view to a matrix size,
removing spikes in the second MR signal, and
weighting k-space data in the second MR signal with a predetermined density compensation factor,
wherein the at least one particular image is generated based on the MR information.