US 11,864,826 B2
Devices and methods for treatment of heart failure by splanchnic nerve ablation
Howard Levin, Teaneck, NJ (US); and Mark Gelfand, New York, NY (US)
Assigned to Axon Therapies, Inc., New York, NY (US)
Filed by Axon Therapies, Inc., New York, NY (US)
Filed on Feb. 9, 2021, as Appl. No. 17/171,447.
Application 17/171,447 is a continuation of application No. 16/510,503, filed on Jul. 12, 2019, granted, now 10,912,610.
Application 16/510,503 is a continuation of application No. 15/017,351, filed on Feb. 5, 2016, granted, now 10,376,308, issued on Aug. 13, 2019.
Claims priority of provisional application 62/112,395, filed on Feb. 5, 2015.
Claims priority of provisional application 62/162,266, filed on May 15, 2015.
Prior Publication US 2022/0000545 A1, Jan. 6, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 18/14 (2006.01); A61N 1/00 (2006.01); A61N 1/36 (2006.01); A61B 18/00 (2006.01); A61B 90/00 (2016.01)
CPC A61B 18/1492 (2013.01) [A61N 1/00 (2013.01); A61N 1/36017 (2013.01); A61B 2018/00214 (2013.01); A61B 2018/00404 (2013.01); A61B 2018/00434 (2013.01); A61B 2018/00791 (2013.01); A61B 2018/00863 (2013.01); A61B 2018/00875 (2013.01); A61B 2090/064 (2016.02)] 13 Claims
OG exemplary drawing
 
13. A method of ablating a greater splanchnic nerve to treat a patient diagnosed with heart failure, comprising:
advancing a guidewire through an azygos vein and into a T9, T10, or T11 intercostal vein;
positioning an endovascular catheter comprising a proximal region, a flexible shaft, and a distal region, wherein the flexible shaft connects the proximal and distal regions and has a length adapted and sufficient to access an azygos vein space of a T9, T10, or T11 vertebra of the patient relative to an access location when the proximal region remains external to the patient, the distal region comprising one or more ablation elements;
advancing the distal region over the guidewire, through the azygos vein into the azygos vein space of the T9, T10, or T11 thoracic vertebra;
activating the one or more ablation elements;
delivering ablative energy to the greater splanchnic nerve using the one or more ablation elements; and
removing the endovascular catheter from the patient.