US 11,864,740 B2
Sample collection and preservation devices, systems and methods
Ridhi Tariyal, Oakland, CA (US); and Stephen K. Gire, Oakland, CA (US)
Assigned to NEXTGEN JANE, INC., Oakland, CA (US)
Filed by NextGen Jane, Inc., Oakland, CA (US)
Filed on Aug. 15, 2022, as Appl. No. 17/888,136.
Application 17/888,136 is a continuation of application No. 16/153,389, filed on Oct. 5, 2018, granted, now 11,446,011.
Application 16/153,389 is a continuation of application No. PCT/US2017/027482, filed on Apr. 13, 2017.
Claims priority of provisional application 62/460,329, filed on Feb. 17, 2017.
Claims priority of provisional application 62/321,987, filed on Apr. 13, 2016.
Prior Publication US 2023/0064804 A1, Mar. 2, 2023
Int. Cl. A61B 10/00 (2006.01); B01L 3/00 (2006.01); C12Q 1/6806 (2018.01); A61B 10/02 (2006.01); A01N 1/02 (2006.01); C12Q 1/6883 (2018.01); C12Q 1/04 (2006.01); C12M 1/30 (2006.01); G01N 1/02 (2006.01)
CPC A61B 10/0045 (2013.01) [A61B 10/0096 (2013.01); B01L 3/00 (2013.01); B01L 3/5029 (2013.01); B01L 3/523 (2013.01); C12Q 1/6806 (2013.01); A01N 1/021 (2013.01); A61B 2010/0006 (2013.01); A61B 2010/0074 (2013.01); A61B 2010/0216 (2013.01); B01L 2200/0621 (2013.01); B01L 2200/16 (2013.01); B01L 2300/069 (2013.01); B01L 2300/0832 (2013.01); B01L 2300/0851 (2013.01); B01L 2400/0683 (2013.01); C12M 33/02 (2013.01); C12Q 1/04 (2013.01); C12Q 1/6883 (2013.01); C12Q 2600/158 (2013.01); G01N 2001/028 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A kit for analysis of a vaginal biological sample, the kit comprising:
(a) a sample collector for collecting a vaginal biological sample; and
(b) an extractor configured to receive and enclose the sample collector, the extractor comprising:
(i) a first chamber configured to receive the sample collector via an opening such that the sample collector is primarily retained in the first chamber;
(ii) a second chamber configured for selective fluid communication with the first chamber,
the second chamber comprising a breakable reagent compartment,
wherein the breakable reagent compartment comprises a solution, said solution configured for preserving, storing, or analyzing the vaginal biological sample; and
(iii) a moveable compression element;
wherein the moveable compression element is configured to close onto the breakable reagent compartment creating a compression force with a projection or surface of the compression element to break the breakable reagent compartment and release said solution, thereby contacting said solution with said vaginal biological sample to form a mixture of said solution and said vaginal biological sample;
wherein said mixture is received in said second chamber;
wherein said mixture is free to flow between said first chamber, said second chamber, and said sample collector after said breakable reagent compartment is broken.