US 11,860,140 B2
Determination of concentrations and amounts of perfluoroalkyl substances by LC/MS/MS
Amanda Comando, Smithtown, NY (US)
Assigned to SUFFOLK COUNTY WATER AUTHORITY, Oakdale, NY (US)
Filed by Suffolk County Water Authority, Oakdale, NY (US)
Filed on May 10, 2022, as Appl. No. 17/662,780.
Application 17/662,780 is a continuation of application No. 16/708,812, filed on Dec. 10, 2019, granted, now 11,360,060.
Prior Publication US 2022/0276209 A1, Sep. 1, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. G01N 30/72 (2006.01); G01N 30/16 (2006.01)
CPC G01N 30/7233 (2013.01) [G01N 30/16 (2013.01)] 22 Claims
OG exemplary drawing
 
1. A method for facilitating detecting PFAS analytes in a sample comprising:
injecting a volume of the sample into an LC/MS/MS system that is configured to detect one or more PFAS analytes of formula CnF(2n+1)—X within an unconcentrated sample;
wherein:
the LC/MS/MS includes ESI;
n is 3, 4, 5, 6, 7, 8 or 9; and
—X is —SO3H, —CO2H, −SO3−, or —CO2−;
subjecting the injected volume of the sample to ESI conditions that include a sheath gas flow of approximately 8 L/min to approximately 12 L/min; and
detecting one or more PFAS analytes within the sample.