US 11,859,256 B2
Stomach cancer detection kit or device, and detection method
Satoko Kozono, Kamakura (JP); Hitoshi Nobumasa, Kamakura (JP); Satoshi Kondou, Kamakura (JP); Hiroko Sudo, Kamakura (JP); Junpei Kawauchi, Kamakura (JP); Atsushi Ochiai, Kashiwa (JP); and Motohiro Kojima, Kashiwa (JP)
Assigned to TORAY INDUSTRIES, LTD., Tokyo (JP); and NATIONAL CANCER CENTER, Tokyo (JP)
Filed by TORAY INDUSTRIES, INC., Tokyo (JP); and NATIONAL CANCER CENTER, Tokyo (JP)
Filed on Sep. 20, 2022, as Appl. No. 17/948,560.
Application 17/948,560 is a division of application No. 16/789,943, filed on Feb. 13, 2020, granted, now 11,486,009.
Application 16/789,943 is a division of application No. 15/319,203, granted, now 10,597,727, issued on Mar. 24, 2020, previously published as PCT/JP2015/067267, filed on Jun. 16, 2015.
Claims priority of application No. 2014-123224 (JP), filed on Jun. 16, 2014; and application No. 2015-071485 (JP), filed on Mar. 31, 2015.
Prior Publication US 2023/0002836 A1, Jan. 5, 2023
Int. Cl. C12Q 1/68 (2018.01); C12P 19/34 (2006.01); C12Q 1/6886 (2018.01); G01N 33/53 (2006.01); C12Q 1/06 (2006.01); G01N 37/00 (2006.01)
CPC C12Q 1/6886 (2013.01) [C12Q 1/06 (2013.01); G01N 33/53 (2013.01); G01N 37/00 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01)] 6 Claims
 
1. A method for detecting stomach cancer in a human subject, comprising:
measuring an expression level of hsa-miR-718 in a blood, serum or plasma sample from the subject;
comparing the measured expression level of hsa-miR-718 to a control expression level for a healthy subject;
detecting an increased level of hsa-miR-718 in the sample from the subject as compared to the control expression level from the sample from the healthy subject;
wherein the increased level of hsa-miR-718 indicates that the subject has stomach cancer; and
wherein the method further comprises treating the subject for the stomach cancer or performing a diagnostic procedure on the subject with the stomach cancer;
wherein the treating comprises surgery, radiotherapy, chemotherapy or a combination thereof; and
wherein the diagnostic procedure comprises gastric X-ray examination, gastroscopy, or imaging of the stomach.