US 11,858,996 B2
Anti-ICOS antibodies
Richard Charles Alfred Sainson, Cambridge (GB); Stephen John Arkinstall, Cambridge (GB); Jamie Iain Campbell, Cambridge (GB); Mohammed Hanif Ali, Cambridge (GB); E-Chiang Lee, Cambridge (GB); Matthew John McCourt, Cambridge (GB); Volker Germaschewski, Cambridge (GB); Ian Kirby, Cambridge (GB); Miha Kosmac, Cambridge (GB); Nahida Parveen, Cambridge (GB); Robert Rowlands, Cambridge (GB); and Gwenoline Borhis, Cambridge (GB)
Assigned to KYMAB LIMITED, Cambridge (GB)
Appl. No. 16/323,980
Filed by Kymab Limited, Cambridge (GB)
PCT Filed Aug. 9, 2017, PCT No. PCT/GB2017/052352
§ 371(c)(1), (2) Date Feb. 7, 2019,
PCT Pub. No. WO2018/029474, PCT Pub. Date Feb. 15, 2018.
Claims priority of application No. 1613683 (GB), filed on Aug. 9, 2016; application No. 1615224 (GB), filed on Sep. 7, 2016; application No. 1615335 (GB), filed on Sep. 9, 2016; application No. 1620414 (GB), filed on Dec. 1, 2016; application No. 1621782 (GB), filed on Dec. 20, 2016; application No. 1702338 (GB), filed on Feb. 13, 2017; application No. 1702339 (GB), filed on Feb. 13, 2017; application No. 1703071 (GB), filed on Feb. 24, 2017; application No. 1709818 (GB), filed on Jun. 20, 2017; application No. 106120562 (TW), filed on Jun. 20, 2017; application No. 106120563 (TW), filed on Jun. 20, 2017; application No. 106120564 (TW), filed on Jun. 20, 2017; application No. PCT/GB2017/051794 (WO), filed on Jun. 20, 2017; application No. PCT/GB2017/051795 (WO), filed on Jun. 20, 2017; and application No. PCT/GB2017/051796 (WO), filed on Jun. 20, 2017.
Prior Publication US 2019/0330345 A1, Oct. 31, 2019
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 16/02 (2006.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01); A61K 47/68 (2017.01); A61K 31/282 (2006.01); C07K 14/55 (2006.01); C07K 16/46 (2006.01); G01N 33/50 (2006.01); A61K 39/00 (2006.01)
CPC C07K 16/2818 (2013.01) [A61K 31/282 (2013.01); A61K 39/395 (2013.01); A61K 47/6849 (2017.08); A61P 35/00 (2018.01); C07K 14/55 (2013.01); C07K 16/2827 (2013.01); C07K 16/468 (2013.01); G01N 33/5026 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); A61K 2039/545 (2013.01); C07K 2317/21 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/40 (2013.01); C07K 2317/52 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/73 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01)] 29 Claims
 
1. An isolated antibody that binds the extracellular domain of human ICOS, comprising a heavy chain amino acid sequence SEQ ID NO: 410 and a light chain amino acid sequence SEQ ID NO: 417.