CPC C07K 16/22 (2013.01) [A61K 47/12 (2013.01); A61K 47/26 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01)] | 24 Claims |
1. An antibody that specifically binds to sclerostin of SEQ ID NO: 1 and comprises a light chain variable region comprising an amino acid sequence set forth in SEQ ID NO: 9 and a heavy chain variable region comprising an amino acid sequence set forth in SEQ ID NO: 10, wherein the antibody comprises two heavy chains, wherein at least one of the heavy chains comprises the amino acid sequence Pro-Ala-Arg-Gly (SEQ ID NO: 8) at the C-terminus of the heavy chain, wherein the C-terminus of one or both of the heavy chains is amidated.
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