CPC C07D 413/12 (2013.01) [A61K 49/0004 (2013.01); C07C 311/47 (2013.01); C07D 209/08 (2013.01); C07D 209/14 (2013.01); C07D 213/42 (2013.01); C07D 233/64 (2013.01); C07D 235/26 (2013.01); C07D 241/04 (2013.01); C07D 271/06 (2013.01); C07D 277/28 (2013.01); C07D 295/26 (2013.01); C07D 307/52 (2013.01); C07D 311/20 (2013.01); C07D 317/66 (2013.01); C07D 403/12 (2013.01); C07D 413/04 (2013.01)] | 36 Claims |
1. A compound of formula (II) or (III), or a pharmaceutically acceptable salt or solvate thereof:
wherein:
R1 is independently selected from the group consisting of hydrogen, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, aryl, heterocyclyl, heteroaryl, cycloalkyl, cycloalkenyl, amino, amido, alkylthio, acyl, arylalkyl and acylamido, all of which may be optionally substituted; and
A is heteroaryl or heterocyclyl, each of which is optionally substituted and linked to the sulfonyl sulphur through a ring nitrogen; and
W2 and R2 form an indacene group or a substituted or hydrogenated variant thereof.
|