US 11,857,962 B2
Systems and methods for sample analysis
Brian Scott Ferguson, Goleta, CA (US); Wentao Shi, Goleta, CA (US); Hui Kang, Goleta, CA (US); Tyler Chozinski, Goleta, CA (US); Jinpeng Wang, Goleta, CA (US); and Qiang Gong, Goleta, CA (US)
Assigned to APTITUDE MEDICAL SYSTEMS, INC., Goleta, CA (US)
Filed by Aptitude Medical Systems, Inc., Goleta, CA (US)
Filed on Aug. 2, 2022, as Appl. No. 17/879,312.
Application 17/879,312 is a continuation of application No. PCT/IB2022/051223, filed on Feb. 11, 2022.
Claims priority of provisional application 63/149,241, filed on Feb. 13, 2021.
Prior Publication US 2023/0027159 A1, Jan. 26, 2023
Int. Cl. B01L 3/00 (2006.01)
CPC B01L 3/502723 (2013.01) [B01L 2200/026 (2013.01); B01L 2200/0689 (2013.01); B01L 2200/141 (2013.01); B01L 2300/042 (2013.01); B01L 2300/044 (2013.01); B01L 2300/047 (2013.01); B01L 2300/0672 (2013.01); B01L 2300/0887 (2013.01); B01L 2300/123 (2013.01); B01L 2300/165 (2013.01)] 13 Claims
OG exemplary drawing
 
1. A container, comprising a sample receptacle and a cap, wherein:
the cap comprises a reservoir for retaining a composition, a first piercing member and a first pierceable barrier for sealing said composition within said reservoir;
the sample receptacle comprises a first open end for receiving a sample, and one or more second piercing members, said first open end is configured for closure by said cap and for receiving said composition;
said first piercing member and said one or more second piercing members are configured to disestablish the first pierceable barrier from opposite side of said first pierceable barrier when said first open end is closed by said cap;
wherein said cap comprises a wall defining the outer perimeter of said reservoir, wherein an outer surface of said wall is made from or is coated with an elastomeric material for sealingly engagement against an inner surface of said sample receptacle when said first open end is closed by said cap;
wherein at least a portion of an interior surface of the sample receptable, configured to be in contact with said wall of the cap when the cap is closed, is made from or is coated with an elastomeric material substantially coextensive with said elastomeric material of the outer surface of the wall; and
wherein pressure inside said container is greater than atmospheric pressure when said first open end is closed and pressed by said cap.