CPC A61N 7/02 (2013.01) [A61N 2007/0004 (2013.01); A61N 2007/0091 (2013.01)] | 18 Claims |
8. A method, comprising:
lysing cells in a target site and substantially preserving an extracellular matrix at the target site by transmitting, by an ultrasound source, pulses of high intensity focused ultrasound having a pulse length in a range of about 1 millisecond (ms) to about 10 ms and a duty cycle in a range of about 1% to about 5%, a focal region of the high intensity focused ultrasound overlapping the target site; and
simultaneously with transmitting the pulses of the high intensity focused ultrasound, perfusing, with a decellularization detergent, vessels of a tissue comprising the target site.
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