CPC A61N 7/00 (2013.01) [A61K 41/0033 (2013.01); C07K 14/705 (2013.01); C12N 13/00 (2013.01); A61B 8/00 (2013.01); A61K 38/00 (2013.01); A61N 2007/0026 (2013.01); G01N 29/00 (2013.01)] | 16 Claims |
1. A method for altering the function or activity of neurons that innervate a targeted tissue portion of a mammalian subject, the method comprising:
applying ultrasound energy to the targeted tissue portion from an ultrasound source, wherein the neurons that innervate the targeted tissue portion are configured to express an exogenous, ultrasound-sensitive transmembrane protein, and
modulating the membrane potential of the neurons innervating the targeted tissue portion and expressing the exogenous, ultrasound-sensitive transmembrane protein to alter the function or activity of the neurons following application of the ultrasound energy.
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