US 11,857,803 B2
Diffusing alpha-emitter radiation therapy with enhanced beta treatment
Lior Arazi, Tel Aviv (IL); Robert B Den, Merion Station, PA (US); Michael Schmidt, Kfar Saba (IL); Ofer Magen, Hod Hasharon (IL); Itzhak Kelson, Tel Aviv (IL); and Amnon Gat, Matan (IL)
Assigned to ALPHA TAU MEDICAL LTD., Jerusalem (IL)
Filed by ALPHA TAU MEDICAL LTD., Jerusalem (IL)
Filed on Dec. 14, 2021, as Appl. No. 17/549,929.
Claims priority of provisional application 63/126,070, filed on Dec. 16, 2020.
Prior Publication US 2022/0184418 A1, Jun. 16, 2022
Int. Cl. A61N 5/10 (2006.01)
CPC A61N 5/1027 (2013.01) [A61N 2005/1085 (2013.01); A61N 2005/1098 (2013.01)] 32 Claims
OG exemplary drawing
 
1. An interstitial source, comprising:
a base suitable for implanting in a tumor;
alpha emitting atoms attached to the base, with a concentration of at least 6 μCi per centimeter length; and
a coating of a low-diffusion polymer covering the alpha emitting atoms in a manner which reduces the desorption probability of daughter radionuclides,
wherein the alpha emitting atoms are attached to the base, with a desorption probability upon radioactive decay of not more than 30%.