US 11,857,623 B2
Pan-antiallergy vaccine
Sari Sabban, Jeddah (SA)
Assigned to King Abdulaziz University, Jeddah (SA)
Filed by King Abdulaziz University, Jeddah (SA)
Filed on Aug. 7, 2020, as Appl. No. 16/988,076.
Prior Publication US 2022/0040296 A1, Feb. 10, 2022
Int. Cl. A61K 39/395 (2006.01); A61K 39/00 (2006.01)
CPC A61K 39/395 (2013.01) [A61K 2039/544 (2013.01); A61K 2039/555 (2013.01)] 14 Claims
 
1. A protein construct, comprising:
a scaffold segment and a motif segment,
wherein the scaffold segment comprises a protein that is exogenous to immunoglobulin E (“IgE”) which has been modified by insertion of the motif segment into the scaffold segment,
wherein the scaffold segment comprises an extracellular adherence protein (EAP) IYN3 chain A (SEQ ID NO: 5), and
wherein the motif segment comprises an IgE FG loop (SEQ ID NO: 2) and
wherein the construct comprises any one of SEQ ID NOS: 7-16.