CPC A61B 5/685 (2013.01) [A61B 5/1459 (2013.01); A61B 5/1473 (2013.01); A61B 5/6868 (2013.01); A61K 41/0028 (2013.01); A61N 1/0502 (2013.01); A61N 1/0529 (2013.01); A61N 1/0551 (2013.01); A61N 5/0601 (2013.01); B21F 45/008 (2013.01); A61B 2562/12 (2013.01); A61N 2005/0612 (2013.01); A61N 2005/0651 (2013.01); B23K 1/0008 (2013.01); B23K 2101/32 (2018.08)] | 42 Claims |
1. A method of making a microneedle comprising a reversible engagement feature, the method comprising:
winding a first length of wire and a second length of wire under tension to generate a primary helix;
brazing the primary helix with a braze material to produce a microneedle comprising the first and second lengths of wire;
fatiguing the first length of wire of the microneedle at its distal end to fracture the first length of wire thereby generating a reversible engagement feature along the second length of wire at the point of fracture.
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